Two MSCs: Marrow stromal cells and mesenchymal stem cells

Two MSCs: Marrow stromal cells and mesenchymal stem cells

Marrow stromal cells are able to generate a series of terminally differentiated cells in vitro. However, most of these experiments are performed with heterogeneous stromal cells, which had been obtained by adherence to plastic culture dishes. Since it is demonstrated that bone marrow-derived stromal cells are purified to a homogeneous population that met the criteria for nonhematopoietic stem cells, these cells have been termed mesenchymal stem cells because they generate an array of cells, defined as mesenchymal cells. In contrast, mesenchymal stem cells are multipotent cells capable of differentiating into cells of mesoderm-origin regardless of cell sources. Mesenchymal stem cells can be recovered from a variety of other adult tissues such as fat, muscle, menstrual blood, endometrium, placenta, umbilical cord, cord blood, skin, and eye. The terms mesenchymal stem cell and stromal cell, both of which are most plausible cells for regenerative medicine, have been used interchangeably in emerging literature; we here re-organize our understanding on two MSC biology and further clinical trail in this review.

Introduction
http://blogs.yahoo.co.jp/akihiroumezawa/19883767.html