The Cure

下に書いてある映画化される（された？）原作の「The Cure」の翻訳権を取ろうと思ったら、ダメだった。ああ。原作は読んだ。ポンペ病の酵素製剤をつくる話。ハリソン・フォードが主演。国立成育医療センターの関連するので、映画も見よう。翻訳じゃなくて、インタビュー形式で、本書こう。出版社を探さなくちゃ。ストーリーは、たくさんある。

Movie Raises Awareness For Pompe Disease Treated At Duke Hospitals

Durham, NC -- There's a good chance you never heard of Pompe Disease before Harrison Ford's new movie 'Extraordinary Measures.' But, the only life-saving treatment for the disease was developed in our state at Duke University Medical Center.

Pompe Disease is when the body lacks an enzyme that breaks down glycogen for energy. That leads to weak muscles, an enlarged heart and trouble moving and breathing.

Doctors at Duke Hospitals treat patients with a drug every two weeks to improve their quality of life. And they say the new movie will raise much-needed awareness.

"The biggest win of course is for the patients because the greater the awareness, the more likely that they are going to be diagnosed and treated early," said Duke Pediatric Geneticist Dr. Priya Kishnani.

‘Extraordinary Measures’ Continue Against Pompe DiseaseReleased: 1/21/2010 1:00 PM EST Embargo expired: 1/21/2010 1:00 PM ESTSource: University of Florida Health Science Center
Dr. Barry Byrne, a pediatric cardiologist and geneticist at the University of Florida College of Medicine, leaves today (Thursday, Jan. 21) for New York, but not for an academic seminar or to present a research paper.

He will be attending the premier of a major motion picture along with Hollywood stars, such as Harrison Ford and Brendan Fraser.

Byrne’s recent brush with movie fame comes as a result of his 15 years of scientific study and clinical trials in efforts to develop treatments for Pompe disease, a rare and complex disorder that is often fatal to children. The film “Extraordinary Measures,” opening Friday, Jan. 22, depicts the true story of how John Crowley, played by Fraser, battles to find a cure to save his two youngest children, who were diagnosed with Pompe.

Ford plays scientist Robert Stonehill, a character based on a collection of researchers associated with the disease, including Byrne, who is the director of UF’s Powell Gene Therapy Center and a member of the UF Genetics Institute.

Faced with no options, Crowley quit his job as a marketing executive and started a biotechnology company, Novazyme Pharmaceuticals Inc., which was eventually purchased by Genzyme Corp.

The original clinical trial for the drug was designed by Byrne and his team at UF. Crowley and his wife Aileen, played by Keri Russell, were prepared to bring their two children to Gainesville for the trial when the pharmaceutical company was acquired by Genzyme.

“The movie focuses on the struggle of John and the scientists he worked with to develop a treatment,” said Byrne, who provided technical expertise and has a brief moment as an extra in the movie. “The filmmakers strived to create a story the audience will understand. I think it will resonate with people to see how much a parent will go through and do anything for his kids.”

Cathryn Mah, Ph.D., a UF assistant professor of pediatrics, has worked with Byrne on gene therapy research and trials for Pompe disease. She attended the Hollywood premier for “Extraordinary Measures” this week.

“It was a very interesting experience,” Mah said. “It was also a little surreal to watch a movie about the research we’ve done and the people we’ve worked with. Never in a million years could I have guessed that a movie would be made out of it.”
Last year Byrne and his son, Tyler, 17, were on the set in Portland, Ore., where they met Ford, Fraser and producer Michael Shamberg (“Erin Brokovich,” “World Trade Center”), who placed Byrne is a couple scenes.“One scene we shot took a half day for what will probably be three seconds.” Byrne said.

Look for the UF physician-scientist during the opening credits, standing next to Fraser on a bus platform wearing a bright blue sweater.